Can a supplement with resveratrol and polyphenols boost cellular energy and metabolism? Researchers at the University of Tennessee, Knoxville and Shaklee Corporation have partnered to address these questions by studying the impact of a unique blend of resveratrol and muscadine polyphenols found in Shaklee VIVIX Cellular Anti-Aging* dietary supplement, on human muscle cell mitochondria, the intra-cellular power plants that generate cellular energy.
With this research, Dr. Jamie McManus, Chairman of Medical Affairs, Health Sciences and Education at Shaklee, and Dr. Michael Zemel of the University of Tennessee are seeking to determine the impact of this unique polyphenol blend on key biological processes related to cellular energy production and aging.
"One of the key mechanisms of aging is a decline in mitochondrial mass as well as the effectiveness of the mitochondria," said Dr. McManus. "In our research, we're trying to validate the impact of VIVIX polyphenols on mitochondrial biogenesis -- shorthand for how the number and size of mitochondria help create cellular energy and boost metabolism. We're excited to share our research goals with the medical community and create a baseline for future studies on polyphenols and cellular energy metabolism."
VIVIX was developed by Shaklee scientists by combining resveratrol with an extract from the only grape in nature that contains an extra chromosome. This muscadine super grape has polyphenols that complement the many benefits of resveratrol. Shaklee scientists created a unique profile of polyphenols shown in laboratory studies to positively impact multiple mechanisms of cellular aging.*
*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
About Shaklee
Founded more than 50 years ago, Shaklee has been a leading provider of premium-quality natural nutrition products, personal care products, and environmentally friendly home care products. In 2000, Shaklee became the first company in the world to be Climate Neutral™ certified to totally offset its CO2 emissions, resulting in a net-zero impact on the environment. With a robust product portfolio, including more than 50 patents and patents pending worldwide, Shaklee has more than 1.25 million Members and Distributors around the globe and operates in the U.S., Mexico, Canada, Japan, Malaysia, Taiwan, and China.
Showing posts with label research. Show all posts
Showing posts with label research. Show all posts
Wednesday, August 11, 2010
Wednesday, November 11, 2009
Just Released: New Vivix Resveratrol Anti-Aging Study
Shaklee just released the results of a new independent Vivix study conducted with a team of scientists at the State University of New York at Buffalo. The goal of this rigorous study was to determine the effects of Vivix on Nrf2, described by Dr. Carsten Smidt as, “the mother of all anti-aging genetic regulators.” Nrf2 activates the body’s detoxification processes, mobilizes antioxidant defenses, triggers anti-stress activity, and strengthens immune balance.
Healthy adults were asked to consume a 910-calorie typical fast food breakfast loaded with saturated and trans fat, carbohydrates, and a little bit of protein. Then the scientific team measured the impact of the meal on Nrf2 activity. With the “food only” group, Nrf2 activity was totally flat to declining over five hours. But the same meal eaten with a serving of Vivix created a massive spike of Nrf2 activity within the first three hours, with a significantly elevated protective level maintained after five hours.
What does this mean? As we age, Nrf2 stops responding when we ingest a high-fat, fast food meal. As a result, such a meal can dramatically increase cellular aging.
The great news is... no matter what diet you eat, Vivix triggers Nrf2 anyway! The better your diet and lifestyle, the better Vivix will work to slow down the aging process!
Purchase Vivix Resveratrol Anti Aging Tonic Online
Wednesday, October 7, 2009
Future Diabetes Treatment May Use Resveratrol To Target The Brain
When this news came across my computer I knew I needed to share it with you. As you might know Shaklee manufactures Vivix an anti-aging resveratrol tonic. Looks like there may be more researched and documented benefits coming down the pike.
Resveratrol, a molecule found in red grapes, has been shown to improve diabetes when delivered orally to rodents. Until now, however, little has been known about how these beneficial changes are mediated in the body. A new study accepted for publication in Endocrinology, a journal of The Endocrine Society, shows that the brain plays a key role in mediating resveratrol's anti-diabetic actions, potentially paving the way for future orally-delivered diabetes medications that target the brain.
Resveratrol activates sirtuins, a class of proteins that are thought to underlie many of the beneficial effects of calorie restriction. Previous studies in mice have provided compelling evidence that when sirtuins are activated by resveratrol, diabetes is improved. Sirtuin activators are now being tested in humans as anti-diabetic compounds.
Sirtuins are expressed virtually everywhere throughout the body and until now, little has been known about what tissues mediate resveratrol's beneficial effects. Knowing where in the body the beneficial effects of activated sirtuins are mediated could help in the development of more effective targeted diabetes medications.
"We know that sirtuins are expressed in parts of the brain known to govern glucose metabolism, so we hypothesized that the brain could be mediating resveratrol's anti-diabetic actions," said Roberto Coppari, PhD, of the University of Texas Southwestern Medical Center and co-author of the study. "To test the hypothesis, we assessed the metabolic consequences of delivering resveratrol directly into the brain of diabetic mice. We found that resveratrol did activate sirtuins in the brain of these mice which resulted in improving their high levels of blood sugar and insulin."
"These findings may lead to new strategies in the fight against type 2 diabetes," said Coppari. "By knowing that the brain mediates resveratrol's anti-diabetic actions, industry can now focus on developing sirtuin activators that directly target the brain. When orally-delivered, these drugs will likely improve diabetes without affecting the other organs in which activation of sirtuins may not always be beneficial."
Other researchers working on the study include Giorgio Ramadori, Laurent Gautron, Teppei Fujikawa, Claudia Vianna and Joel Elmquist of the University of Texas Southwestern Medical Center in Dallas, Tex.
The article, "Central administration of resveratrol improves diet-induced diabetes," will appear in the December 2009 issue of Endocrinology.
Buy Vivix Online
Resveratrol, a molecule found in red grapes, has been shown to improve diabetes when delivered orally to rodents. Until now, however, little has been known about how these beneficial changes are mediated in the body. A new study accepted for publication in Endocrinology, a journal of The Endocrine Society, shows that the brain plays a key role in mediating resveratrol's anti-diabetic actions, potentially paving the way for future orally-delivered diabetes medications that target the brain.
Resveratrol activates sirtuins, a class of proteins that are thought to underlie many of the beneficial effects of calorie restriction. Previous studies in mice have provided compelling evidence that when sirtuins are activated by resveratrol, diabetes is improved. Sirtuin activators are now being tested in humans as anti-diabetic compounds.
Sirtuins are expressed virtually everywhere throughout the body and until now, little has been known about what tissues mediate resveratrol's beneficial effects. Knowing where in the body the beneficial effects of activated sirtuins are mediated could help in the development of more effective targeted diabetes medications.
"We know that sirtuins are expressed in parts of the brain known to govern glucose metabolism, so we hypothesized that the brain could be mediating resveratrol's anti-diabetic actions," said Roberto Coppari, PhD, of the University of Texas Southwestern Medical Center and co-author of the study. "To test the hypothesis, we assessed the metabolic consequences of delivering resveratrol directly into the brain of diabetic mice. We found that resveratrol did activate sirtuins in the brain of these mice which resulted in improving their high levels of blood sugar and insulin."
"These findings may lead to new strategies in the fight against type 2 diabetes," said Coppari. "By knowing that the brain mediates resveratrol's anti-diabetic actions, industry can now focus on developing sirtuin activators that directly target the brain. When orally-delivered, these drugs will likely improve diabetes without affecting the other organs in which activation of sirtuins may not always be beneficial."
Other researchers working on the study include Giorgio Ramadori, Laurent Gautron, Teppei Fujikawa, Claudia Vianna and Joel Elmquist of the University of Texas Southwestern Medical Center in Dallas, Tex.
The article, "Central administration of resveratrol improves diet-induced diabetes," will appear in the December 2009 issue of Endocrinology.
Buy Vivix Online
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